Výsledky projektu

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krahulik
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Registrován: úte 09 led, 2007 10:33

Re: Výsledky projektu

#1 Příspěvek od krahulik » pon 28 pro, 2009 12:49

  • Jak bylo avizovano, projekt (jeho prvni faze) byl oficialne ukoncen k 22. 10. 2009, pricemz projekt byl spusten dne 5. 5. 2009. Za tu dobu pres 67 tis. uzivatelu zpracovalo pres 3 miliony vysledku, coz predstavuje temer 3 tis. let vypocetniho vykonu priblizne 150tis. pocitacu. Ukoncenim 1. faze byl projekt presunut z aktivnich do ukoncenych.

    Pomoci programu zvaneho AutoDock, ktery byl pro prvni fazi navrzen k zobrazeni moznych interakci asi 3 milionu sloucenin s proteiny kmenu chripkoveho viru (vcetne kmenu rezistentnich vuci lekum a H1N1) potrebnych k replikaci a sireni v tele. Asi 2000 z nejnadejnejsich kandidatu budou zkoumany v 2. fazi projektu k eliminaci rady falesnych pozitivnich vysledku.

    Pri druhe fazi projektu se pro detailnejsi vyzkum techto kandidatu bude pouzivat program s nazvem CHARMM. Testovani sloucenin v laboratori by bylo velmi nakladne, casove narocne a neefektivni. Pomoci vypocetniho vykonu World Community Grid bude tento vyzkum vyrazne urychlen.

    Nyni maji vedci plne ruce prace s post-processingem vysledku 1. faze a s pripravou 2. faze. Vice aktualnich informaci od hlavniho vedeckeho pracovnika Stana Watowiche naleznete v tomto vlakne.

    Jmenem projektoveho tymu pri University of Texas Medical Branch Vam chceme vyjadrit sve uprimne podekovani za prispeni Vaseho vypocetniho vykonu tomuto projektu. Vasim prispevkem byla tato faze projektu dokoncena za zlome casu, ktery by byl jinak zapotrebi.

    Do doby nez dojde ke spusteni druhe faze, potrebujeme Vasi pomoc v ostatnich aktivnich projektech. Vsechny tyto dulezite projekty vyzaduji Vas pocitacovy cas.
EDIT:
Souhrnne info 1. faze
start: 5. 5. 2009
konec: 22. 10. 2009
pocet vysledku: 3 848 185
vypocetni cas (CPU): 2 876 let

Influenza Antiviral Drug Search (Phase 1) Completion

World Community Grid is pleased to announce that as a result of the generous contribution of computing power from our members, Phase 1 of The Influenza Antiviral Drug Search project finished on October 22, 2009.
The project launched on May 5, 2009. During that time over 67,000 members processed over 3 million results which required almost 3,000 years of computing power from about 150,000 computers.
As part of ending Phase 1 of the project, it has been moved from Active Research to Completed Research on the Research pages and in the Forums.

Utilizing a program called AutoDock, Phase 1 of this project was designed to screen about 3 million compounds for their possible interaction with proteins required by strains of the influenza virus (including drug resistant strains and H1N1) to replicate and spread in the body. About 2,000 of the most promising candidates will be further screened in Phase 2 to eliminate many false positives.

Phase 2 of the project will use a program called CHARMM to perform a more refined screening of the 2,000 candidates obtained in Phase 1. Testing these in the laboratory would be very costly, time consuming, and inefficient. Using the computational power of World Community Grid will greatly accelerate this research.

At this time, the researchers are busy performing post-processing on the results from Phase 1 and are preparing for Phase 2. You may read about these plans and get the latest update from the Principal Investigator, Stan Watowich, in the following forum thread: http://www.worldcommunitygrid.org/forum ... read,27840

On behalf of the Influenza Antiviral Drug Search project research staff at the University of Texas Medical Branch, USA, we wish to express our sincere gratitude to you for contributing your computer power to this project. With your contribution, this phase of the project was completed in a fraction of the time it would otherwise have taken.

While we wait for Phase 2 to start, we still need your help with six (6) other ongoing projects! World Community Grid continues to run the Help Cure Muscular Dystrophy - Phase 2, Help Fight Childhood Cancer , Nutritious Rice for the World , Help Conquer Cancer , Human Proteome Folding - Phase 2 and FightAIDS@Home . All of these important projects need your computer time.
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